The most prepared college graduates are the ones that already started building their network the moment they picked a major. It's not impossible to find a job if you don't do this, but it certainly makes it a lot harder. Not that anything is truly easy in these tough economic times. It's because of this difficult job market that college grads need to have a solid plan when searching for work.
Being prepared means being extremely organized. Consider creating a spreadsheet that keeps track of all of the jobs you have applied for. Organizations will often post their open positions on multiple job boards, so it's important to make sure you aren't applying to the same job twice. This is not only a waste of your time but also could disqualify your initial application.
Another important thing to do is to have realistic expectations about the work you need to do. Just because you have the most impressive resume in the world doesn't mean you don't have to put any effort into your hunt. With the amount of competition that is out there, you will need to be vigilant to ensure that you get the job that you want.
These are just some of the tips that will help ease the job search for college graduates. If you have any others, feel free to share them. Best of luck to all of the future members of the work force!